The Faculty of Medicine, Fayoum University, the Japan
International Cooperation Agency (JICA), and the Egyptian Fund
for Technical Cooperation with Africa (EFTCA), agreed in June
2009, to work together to establish a training course directed
for clinical immunology of infectious diseases. The course will
be held at FOM/FU, Fayoum, under JICA's Third-Country Training
Participants of this course will primarily include the African
researchers who are involved in training or supervision of staff
working in the field of laboratory medicine & immuno-diagnosis.
The course is designed mainly for bench worker physicians
and bioscientists to upgrade their practice
and research capabilities, including research design. More
than 35% of the course agenda are practical laboratory work.
This course will be held annually.
The objectives of the course are to provide African participants
working in the field of laboratory diagnosis of infectious
diseases, whose special interest is the clinical Immunology,
with the recent information in their field of work, to
interchange their own experiences together, and to be able to
contribute to the development of clinical immunology research in
the participating countries of Africa.
The course will be held at Fayoum University (FU), Fayoum City,
under JICA's Third-Country Training Program (TCTP).
International Course for Clinical Immunology
for Infectious Diseases (ICCI) for Nile Basin Countries.
Website of the Course:
Duration of the Course:
• Five (5) weeks every year from 2009 to 2011.
• The 16th program will be organized from September 5th to
October 16th 2011.
The Governments of the following countries will be invited to
apply by nominating their applicants for the course: Burundi,
Comoros, Democratic Republic of the Congo, Djibouti, Ethiopia,
Eritrea, Kenya, Malawi, Mauritius, Rwanda, Seychelles, Sudan,
Swaziland, Tanzania, Uganda, Zambia and Zimbabwe.
Number of Participants:
The total number of participants will be twenty (20),
seventeen (17) from African countries, and three (3) from Egypt.
The role of infectious diseases in threatening the
human life has been re-expanded. The emergence of new infectious
diseases, AIDS, ALT, Hepatitis C virus, Ebola virus, SARS, Avian
Influenza and H1N1 Influenza; received a special world wide
attention, because of their current and potential hazards to the
health of the world population.
The role of laboratory diagnosis and monitoring of such diseases
is of utmost importance for prevention. Most of the African
countries are in a situation where infectious diseases represent
the major health menace. The challenges posed by this problem
entail fund raising for appropriate diagnosis and control of
such infections and to have the technical expertise to carry out
Egypt, as one of the African countries, has good potentials to
be a center for manpower development in the field of health
upgrading programs. These potentials include its central
geographical position in the old world, good framed heath
system, with one of the oldest Schools of medicine in the
African continent. However, the most important issue is that
Egypt shares with the other African countries their common
health problems, especially the infectious diseases. In Egypt,
one can say that there is a sound basic medical research
Objective Setting of the Course:
The course is
designed to provide opportunities for participants to enhance
their current technical skills in laboratory medicine and
research capabilities in the field of infectious diseases. The
course will help maximizing the contribution of participants to
their countries health development, especially in the field of
protection against infectious diseases, through the laboratory
(Expected learning outcomes of the
At the end of the course, the participants are expected to have
• Basic information of fundamental immunology.
• Recent information on natural history and pathophysiology of
• Hands-on experience in running and development of medical
laboratory for diagnosis of infectious diseases.
• Basic Knowledge and usage of standard immunological techniques
in evaluating diagnostic tests and decision analysis.
• Basic concepts for both quality management philosophy for
organizational development and a management process for
improving the quality of all aspects of laboratory work,
especially in the direction of communicable diseases.
• To acquire concepts and basis for the application of total
quality management applied to laboratory medicine (immunology
• To be introduced to the 5S and to evaluate its relevance in
the continuous improvement of quality of laboratory work and
Methodology used in conducting the Course:
The course will be conducted in the form of Lectures (L),
Practices (P), Field-trips (F), Group Studies (G), Work Shops
(W) & small group discussions.
Tentative Curriculum of the
The curriculum scheme
I. LECTURES (L):
1) Fundamental Immunology
• Immunology: An overview2)
Immunity to Viruses & Bacteria.
• Adaptive & Innate Immunology
• Cells involved in the immune response
• Cell mediated immunity
• Humoral immunity
• Antigen recognition
• Cell interaction in the immune system
• Regulation of the immune system
• MHC and Genetic control of immune system
6) Principles and interpretation of some important Immunological
7) Hepatitis B and C viruses.
8) AIDS and ALT.
9) Introduction to Molecular Biology.
10) Introduction to Medical Statistics.
11) Quality control and quality assurance
- Basic Concepts;
- Framework of total quality management in a health care lab;
- Quality Laboratory processes (QLPA);
- Quality Control (QC);
- Quality Assessment;
- Quality Planning (QP);
- Elements of quality assurance program;
- Pre-analytic variables: control & monitoring;
- Control of Analytic Variables;
- Control of Analytic Quality;
- External Quality program in Medical Laboratory;
- Economic of making diagnosis;
- The 5S principles for TQM in health.
II. PRACTICES (P):
1. Immunological Techniques.
• Neutrophil phagocytosis.
• Complement assay by RID.
• Immunofluorescence detection of auto-antibodies.
• Rapid testing for HIV & HBsAg.
• Immunoblot confirmatory diagnosis of HCV.
• Automated Fluorescent DNA sequencing.
• ELISA Technique: Diagnosis of viral hepatitis.
• PCR of HCV- RNA.
• Flowcytometer CD4+/8+ assay.
• Flowcytometer intracellular cytokine assay.
• Innolia for ANA.
• HLA Typing.
• PC Statistics Package.
• Real Time PCR in immunogenetic of infectious diseases.
• Processing of samples on Bactec TB.
• Neuroimmunology of Infectious Diseases.
III. FIELD-TRIPS (F):
1- Primary Health Care Centers in Fayoum.
2- National Central lab (Cairo).
IV. GROUP STUDY (G):
Problem solving & working in small groups and brain
storming sessions will be the style of working to elaborate
ideas and to train the participants to work in groups.
V. PRESENTATION BY THE PARTCICPANTS (R):
Each participant from the invited countries will present a
comprehensive report on the activities he/ she is currently
taking at home emphasizing the means through which the course
may help in improving conditions of his/ her activities.
VI. THREE WORKSHOPS (W):
- Total Quality Management
These intensive workshops will help participants grasping
essentials for development of a research protocol. The following
topics will be emphasized in the workshop: Research design;
Sources of bias in medical research; Measurements & types of
error; Inter-observer & Intra-observer disagreement; Data
management; How to use a simple computer package for statistical
analysis of data.
- Research Methodology
• The above curriculum may be subjected to some changes.
Main Training Institution:
Faculty of Medicine/ Fayoum University, (FOM/ FU),
Fayoum University was established in 1983 as a branch of Cairo University.
In 2005 the university was separated as an independent
university according to the decree number (48). Fayoum
University includes 13 faculties: Faculties of Education,
Agriculture, Engineering, Archaeology, Medicine, Arts,
Informatics & computer Sciences and Faculty of Kindergarten. The
university embraces around 25 thousand students and about two
thousand of teaching staff members. The main core of the course
will take place at the FOM/FU at the University Teaching
Hospital, Fayoum - Egypt. The University Hospital was
established in 2008. The Hospital has 350 beds and provides
comprehensive services in out-patient and in-patient
Supporting and Collaborating Institutions and Agencies:
• Kumamoto National Hospital, 1-5 Ninomaru, Kumamoto City 860,
• Kumamoto University Medical School 2-1 Honjoh, Kumamoto
City 860, JAPAN.
• Federation of African Immunological Societies (FAIS) :
• International Union of Immunological Societies (IUIS):
Completion Certificate:Participants who have successfully
completed the course will be awarded a certificate of
attendance the course.