Faculty of Medicine

Prof. Amr Aly Ibrahim Zahra

Contact Information
Phone Number: 084 2146315                          
Fax Number: 084 2160180
E-mail Address: aaz00@fayoum.edu.eg
Office: Faculty of Medicine, 3th floor, Medical Biochemistry and Molecular Biology department.
Post Address: Fayoum, fayoum university, faculty of medicine, Medical Biochemistry and Molecular Biology department, Postal code: 63514
Academic Qualifications
M.B., B.Ch.: Faculty of Medicine, Cairo University, 1994: Excellent with degree of honor
M. Sc. Medical Biochemistry and Molecular Biology: Master degree in Basic Medical Sciences (Biochemistry–Biochemistry), Faculty of Medicine, Cairo University, November 1999
M.D. Medical Biochemistry and Molecular Biology: M.D. in Basic Medical Sciences (Medical Biochemistry), Faculty of Medicine, Cairo University, November 2002.
Academic Positions
Demonstrator in medical biochemistry department. Faculty of Medicine, 6 October University: 1996-1997.
Demonstrator in medical biochemistry department, Faculty of Medicine, Cairo University (Beni Suef Branch): 1997-2000.
Assistant Lecturer of medical biochemistry. Faulty of Medicine, Cairo University (Beni Suef Branch): 2000-2003
Lecturer of medical biochemistry, Faculty of Medicine, Cairo University (Beni Suef Branch): 2003 to 2004.
Lecturer of medical biochemistry, Faculty of Medicine, Cairo University (Fayoum Branch): 2004 to 2006.
Lecturer of medical biochemistry. Faculty of Medicine, Fayoum University: 2006 to 2008.
Assistant professor and Head of medical biochemistry department. Faculty of Medicine, Fayoum University: 2008 to 2018.
professor :From 2018 Until Now.
Thesis
Endothelial Dysfunction In Obese Females
The Predictive Value Of Urinary Deoxypyridinoline As A Marker For Osteoporosis In Postmenopausal Women.
Research Interests
Environmental diseases and role of biochemistry in their diagnosis.
Genetic diseases and role of biochemistry in their diagnosis.
New discoveries related to diseases and role of biochemistry in their use.
Modern applications in medicine and their relationship to biochemistry
Scientific Publications
Impact of Chronic Noise Exposure on Stress, Cardiovascular System and Auditory System among Marble and Granite Workers. Egyptian Journal of Occupational Medicine, 2004; 28 (2):327-344.
Renal Tubular Dysfunction in Chronic Low-Level Cadmium Exposure Among Smokers. Egyptian Journal of Occupational Medicine, 2005; 29 (I): 271-282.
Blood Antioxidants in Active as well as Passive and Non-Smoker Healthy Male Subjects: Relation to Urinary Cotinine. The Egyptian Journal of Biochemistry and Molecular Biology, 2005; 23:584-603.
Detection of FXIII V34L Polymorphism by Modified PCR-RFLP and its Association with Intracranial Hemorrhage and Venous Thrombosis. The Egyptian Journal of Laboratory Medicine, 2005; 17 (1,2): 99-110.
Association between Plasma Adiponectin, TNF-? and NAFLD in Egyptian Male Patients. The Egyptian Society of Basic Medical Sciences; June 2005; 26 (suppl. I): 17-29.
Role of Neurokinin B Peptide in Preeclamptic Pregnant Women; The Neurovascular Theory. The Journal of the Egyptian Society of Obstetrics and Gynecology; 2005; 31 (10,11,12): 897-910.
Prediction of Pre-Eclampsia by Combining Serum Activin-A and Inhibin- A to Early Diastolic Notch of Uterine Artery Doppler Waveforms. The Journal of the Egyptian Society of Obstetrics and Gynecology, 2005; 31 (10,11,12): 897-910.
Association of Gerrelin and Resistin With Body Fat Composition and Insulin Resistance in Chronic Renal Failure. Bulletin of Egyptian Society for Physiological Sciences, 2007; 27 (2); 249-264.
The Relation between Major Depression and Plasma levels of Cytokines and High Sensitivity CRP. Bulletin of Egyptian Society for Physiological Sciences, 2007; 27 (2): 307-316.
Natural Killer Cells and Zinc Deficiency among Children with Intestinal Parasitic Infections. The Egyptian Journal of Cairo University, 2007; 25 (4); 335-341.
Paraoxonase I Activity and Polymorphism in Egyptian Lead-Exposed Workers. The Egyptian Journal of Biochemistry and Molecular Biology, 2008; 26: 262-285.
Osteopontin Gene Polymorphisms as Predictors for the Efficacy of Interferon Therapy in Chronic Hepatitis C Egyptian Patients with Genotype 4
Role of ICAM-1 and E-selectin gene polymorphisms in pathogenesis of PAOD in Egyptian patients. Vasc Health Risk Manag. 2010; 6: 9–15.
 25-Hydroxy-vitamin D3 level is a predictor to insulin resistance in patients with hepatitis C virus-induced liver cirrhosis. Egypt J Intern Med 2013; 25:63–69..
   P16 epigenetic changes associated with H. pylori infection in cancerous and noncancerous gastric lesions. Journal of Medical Molecular Biotechnology "JMMB" 2013; 11(1): 1-16
The Influence of A118G Single Nucleotide Polymorphism of Human Mu Opioid Receptor Gene and the MDR1 Gene in Egyptian Patients With Tramadol-induced Seizure. Addictive Disorders & Their Treatment. 2015; 14(2): 105-112.
   Association of Angiotensin-Converting Enzyme (ACE) Gene Polymorphism with Inflammation and Cellular Cytotoxicity in Vitiligo Patients. PLoS One 2015;10(7):e0132915.
Possible Role of LAPTM4B Polymorphism as Biomarker for Hepatocellular Carcinoma in Egyptian Patients. Med. J. Cairo Univ., Vol. 83, No. 2, June, 2015: 105-111.
   Relationship between Serum LAPTM4B Protein and Susceptibility to Hepatocellular Carcinoma. Med. J. Cairo Univ., Vol. 83, No. 1, June, 2015:529-534..
 Serum Vitamin D as a Predictor to the Response of Interferon Therapy in HCV Genotype 4. Med. J. Cairo Univ., Vol. 83, No. 2, September, 2015: 1-6.
 Hepatocyte-Derived MicroRNAS as Serum Predictors of Rejection of Liver Transplantation. Med. J. Cairo Univ., Vol. 83, No. 2, September, 2015: 103-108
  Polymorphism in 1-α Hydroxylase CYP27B1-1260 in Egyptian Patients with Chronic Hepatitis C Virus Genotype 4 and their Effect on the Response to Interferon Therapy. Med. J. Cairo Univ., Vol. 83, No. 1, September, 2015: 645-650.
   Serum YKL-40 as a Biomarker in Egyptian Breast Cancer Females. Med. J. Cairo Univ., Vol. 83, No. 2, December, 2015: 9-16. .
Identification of Single Nucleotide Polymorphisms in Myxovirus Resistance-1 (MxA) Gene Promoter (C/A at NT- 123) Correlated with the Response of Hepatitis C Patients to Interferon. Med. J. Cairo Univ., Vol. 83, No. 2, December, 2015: 71-77.
   Circulating MicroRNAs, miR-122, miR-148a, and miR-194, in Patients with Hepatocellular Carcinoma Emerging from a Chronic HCV Infection Background . Med. J. Cairo Univ., Vol. 83, No. 1, December, 2015: 805-810. .
   Possible Role of Chitinase-3-Like Protein 1 (YKL-40) Polymorphism as Diagnostic Biomarker of Breast Cancer in Egyptian Female Patients. Med. J. Cairo Univ., Vol. 83, No. 1, December, 2015: 851-857.
 Identification of Single Nucleotide Polymorphisms in Myxovirus Resistance-1 (MxA) Gene Promoter (G/T at NT-88) Correlated with the Response of Hepatitis C Patients to Interferon. Med. J. Cairo Univ., Vol. 83, No. 1, December, 2015: 1043-1050..
   MicroRNAs as Promising Novel Biomarkers for Diagnosis of Breast Cancer Med. J. Cairo Univ., Vol. 84, No. 2, September, 2016: 263-269. .
Down Regulated Micro RNA-145 as a Marker to Diagnose Breast Cancer in Egypt Med. J. Cairo Univ., Vol. 84, No. 1, September, 2016: 1113-1118..
 Impact of FokI (rs10735810) and BsmI (rs1544410) on Treatment of Chronic HCV Patients With Genotype 4. J Clin Lab Anal. 2016 Nov;30(6):1021-1027.
  Vitamin D Receptor FokI Gene Polymorphism Predicted Poor Response to Treatment in Chronic HCV Genotype 4. International Journal of Biomedicine 6(4) (2016) 265-270..
  The Coincidence of ACE Gene Polymorphism with Occult HBV Infection in Egyptian Patients with End-Stage Renal Disease. Arab J. Lab. Med. 2018; 43 (2): 285-296.
  Implications of Methylated SFN Gene and MiRNA-200c on Pathogenesis of Breast Cancer. Arab J. Lab. Med. 2018; 43 (2): 297-310..
Gene Expression of Matrix Metalloproteinase-1 and Growth Differentiation Factor-5 in Patients with Knee Osteoarthritis Before and After Treatment
The Longevity Gene SIRT1 Polymorphisms rs7895833 and rs2273773 and Long-Term Survival in Patients with Rheumatoid Arthritis
Member of the following Organizations
The Egyptian Society of Biochemistry
The Egyptian Medical Molecular Biology and Biotechnology..
Conferences
The 8th International Conference of Oncology, Gastrointestinal Malignancies. Faculty of Medicine, Suez Canal University, Stella De Marie, 21-23 April, 2004.
Annual Scientific Congress of The Egyptian Society of Biochemistry and Molecular Biology (ESBMB) entitled “Implication of Biochemistry and Molecular Biology in Health and Disease”, arranged by Faculty of Medicine, Cairo University, 24-25 April, 2004.
Annual Scientific Congress of The Egyptian Society of Biochemistry and Molecular Biology (ESBMB) entitled "Molecular Biology and Environmental Factors in Health and Disease", arranged by Faculty of Medicine, Ain Shams University, 28-29 April, 2005.
The 3rd Egyptian International Conference on Living Donor Liver Transplantation "LDLT", organized by Scientific Committee, Liver Transplantation Center, Dar Al Fouad Hospital, Cairo, Egypt, 5-7 April, 2006.
Annual Scientific Congress of The Egyptian Society of Biochemistry and Molecular Biology (ESBMB) entitled "New Horizons in Molecular Biology, Biotechnology and Environmental Promotion", arranged by Faculty of Medicine, Ain-Shams University, 19-21 April, 2006.
The 18th International Conference of The Egyptian Society of Laboratory Medicine (ESLM) entitled "The Laboratory: From Self-Education to Accreditation" arranged by Cairo International Conference Center-Nasr City, Cairo, Egypt, 21-22 March, 2007.
Annual Scientific Congress of The Egyptian Society of Biochemistry and Molecular Biology (ESBMB), arranged in Cairo, Egypt, 19-20 April, 2007.
The 55th Scientific Congress of The Egyptian Society of Clinical Chemistry (ESCC) "International Meeting" entitled "Improving Health Care Through Laboratory and Personalized Medicine", Cairo Mariott Hotel, Cairo, Egypt, 19-20 January, 2008.
The 1st Scientific Conference of Medical Biochemistry Department- Faculty of Medicine, Mansoura University in collaboration with The Egyptian Society of Biochemistry and Molecular Biology (ESBMB), Held on 14 February 2008.
The 35th Annual International Congress of The Egyptian Society of Cardiology, Fairmont Heliopolis Hotel, Cairo, Egypt, 25th -29th February 2008.
Teaching Experience
 Supervision of and participation in the teaching of medical biochemistry curriculum (theoretical & practical) for the first and second year students, Faculty of Medicine - Fayoum University..
Supervision of and participation in the teaching of medical biochemistry curriculum (theoretical & practical) for the first year students, Faculty of Dentistry- Fayoum University.
 Supervision of and participation in the teaching of medical biochemistry curriculum (theoretical & practical) for the first year students, Faculty of Nursing - Fayoum University
 Supervision of and participation in the teaching of medical biochemistry curriculum (theoretical & practical) for the first year students, Institute of Nursing - Fayoum University.
  Supervision of and participation in the teaching of medical biochemistry curriculum for the clinical master degree students, Faculty of Medicine - Fayoum University
Supervision of and participation in the teaching of medical biochemistry curriculum for the master & M.D. degree students, Faculty of Medicine - Fayoum University
  Supervising the scientific review articles and seminars for the master & M.D. degree students in Medical Biochemistry, Faculty of Medicine, Fayoum University.
 Teaching of Medical Biochemistry curriculum (theoretical & practical) for the first and second year students, Faculty of Medicine - Cairo University (both Kasr al-Aini and Beni Suef branch).
  Teaching of Medical Biochemistry curriculum (theoretical & practical) for the first year students, Faculty of Dentistry - Cairo University.
Examination Experience:
  Preparing written, oral and practical examinations for first and second year students, Faculty of Medicine- Fayoum University.
   Preparing written, oral and practical examinations for first year students, Faculty of Dentistry- Fayoum University.
 Preparing written, oral and practical examinations for first year students, Faculty of Nursing - Fayoum University.
  Preparing written, oral and practical examinations for first year students, Institute of Nursing - Fayoum University.
Preparing written, oral and practical examinations for master & M.D. degree students, Faculty of Medicine - Fayoum University.
   Preparing written, oral and practical examinations for master & M.D. Medical Biochemistry degree students, Faculty of Medicine - Fayoum University.
Supervision of the Theses
Supervising of 11 master theses and 9 doctoral theses.
Training Courses
Attending a training program on "Molecular Diagnostics" held by the Unit of Biochemistry & Molecular Biology (UBMB), Faculty of Medicine, Cairo University, 3-15 May, 2003.
Attending a training program on "Ethics" in Medical Education Development Center, Faculty of Medicine, 2-4 April, 2007. Financed by Faculty and Leadership Development Project, Cairo University
 Attending a training program on "Scientific writing and International Publishing" in Medical Education Development Center, Faculty of Medicine, 9-11 April, 2007. Financed by Faculty and Leadership Development Project, Cairo University.
 Attending a training program on "Teaching on Large Scale and Small Scale" in Medical Education Development Center, Faculty of Medicine, 16-18 April, 2007. Financed by Faculty and Leadership Development Project, Cairo University.
   Attending a training program on "Thinking Skills" in Medical Education Development Center, Faculty of Medicine, 22-24 April, 2007. Financed by Faculty and Leadership Development Project, Cairo University.
  Attending a training program on "Quality Assurance and Control" in Medical Education Development Center, Faculty of Medicine, 22-24 April, 2007. Financed by Faculty and Leadership Development Project, Cairo University.
 Attending a training program on "Time Management and Work Stress" in Medical Education Development Center, Faculty of Medicine, 22-24 April, 2007. Financed by Faculty and Leadership Development Project, Cairo University.
Activities
Genetic Predictors of Response to Interferon Therapy in HCV Patients. Project No. 1512 (PI: Prof. Dr. Olfat G. Shaker), funded by the Egyptian Science and Technology Development Fund (STDF).
TEMPUS projects at Fayoum University.