Faculty of Medicine

Dr. Wael Botros Abu-Alyamin Ghaly

Contact Information
Phone Number: 084 6300587                          
Fax Number: 084 6302350
E-mail Address: wba00@fayoum.edu.eg
Office: Bulding Of Faculty Medicine - Physiology Department
Post Address: Fayoum University - Faculty of Medicine - Physiology Department - POBox: 63514
Academic Qualifications
B. Sc. : Bachelor of Medicine and Surgery- Cairo University -2002
M. Sc. : Medical Physiology - Cairo University - 2009
Ph.D. : Medical Physiology - Cairo University - 2016
Academic Positions
Demonstrator : From 2005 to 2009
Assistant Lecturer : From 2009 to 2016
Lecturer : From 2016 Untill Now
Assistant Professor : From 2023 Untill Now
Research Interests
GIT hormones and their effect on glucose homeostasis
neuroendocrinology
GIT Hormones regulatory effect on the appetite
Antiapoptotic
Theses
CARDIOPROTECTIVE EFFECTS OF ERYTHROPOIETIN HORMONE: A STUDY ON A POSSIBLE ROLE IN HEART FAILURE AND MYOCARDIAL INFARCTION: ELUCIDATION OF UNDERLYING MECHANISMS.
Nephroprotective Effect of Erythropoietin in Diabetic Rats : Evaluation of possible underlying mechanisms.
Publications
Darwish NM, Elshaer MMA, Almutairi SM, Chen T-W, Mohamed MO, Ghaly WBA, Rasheed RA. Omega-3 Polyunsaturated Fatty Acids Provoke Apoptosis in Hepatocellular Carcinoma through Knocking Down the STAT3 Activated Signaling Pathway: In Vivo and In Vitro Study. Molecules. 2022; 27(9):3032.
Panagiotou G, Ghaly W, Upadhyay J, Pazaitou-Panayiotou K, Mantzoros CS. Serum Follistatin Is Increased in Thyroid Cancer and Is Associated With Adverse Tumor Characteristics in Humans. J Clin Endocrinol Metab. 2021 Apr 23;106(5):e2137-e2150.
N Perakakis, A Kokkinos, A Joshi, N Peradze, N Tentolouris, W Ghaly, D Tsilingiris, A Alexandrou, C Mantzoros. Regulation of the activin-follistatin hormonal system in relation to glucometabolic status in mice, in healthy humans and in obese individuals undergoing bariatric surgery, Diabetologie und Stoffwechsel 2021; 16(S 01): S70.
Polyzos SA, Perakakis N, Boutari C, Kountouras J, Ghaly W, Anastasilakis AD, Karagiannis A, Mantzoros CS. Targeted Analysis of Three Hormonal Systems Identifies Molecules Associated with the Presence and Severity of NAFLD. J Clin Endocrinol Metab. 2020 Mar 1;105(3).
Perakakis N, Kokkinos A, Peradze N, Tentolouris N, Ghaly W, Tsilingiris D, Alexandrou A, Mantzoros CS. Metabolic regulation of activins in healthy individuals and in obese patients undergoing bariatric surgery. Diabetes Metab Res Rev. 2020 Jul;36(5):e3297. doi: 10.1002/dmrr.3297. Epub 2020 Mar 1. PMID: 32026536.
Perakakis N, Kokkinos A, Peradze N, Tentolouris N, Ghaly W, Pilitsi E, Upadhyay J, Alexandrou A, Mantzoros CS 2019 Circulating levels of gastrointestinal hormones in response to the most common types of bariatric surgery and predictive value for weight loss over one year: Evidence from two independent trials. Metabolism - Clinical and Experimental, 101, 153997.
Perakakis N, Kokkinos A, Peradze N, Tentolouris N, Ghaly W, Tsilingiris D, Alexandrou A, Mantzoros CS. Follistatins in glucose regulation of healthy and obese subjects. Diabetes Obes Metab. 2019 Mar;21(3):683-690.
Assistant Lecturer : From 2009 to 2016
Perakakis N, Mougios V, Fatouros I, Siopi A, Draganidis D, Peradze N, Ghaly W, Mantzoros CS. Physiology of activins/follistatins: associations with metabolic and anthropometric variables and response to exercise. J Clin Endocrinol Metab.2018 Oct 1;103(10):3890-3899.
Perakakis N., Upadhyay J., Ghaly W., Chen J., Chrysafi P., Anastasilakis AD., Mantzoros CS. Regulation of the activins-follistatins-inhibins axis by energy status: Impact on reproductive function. Metabolism. 2018 Aug;85:240-249.
Upadhyay J., Farr O., Perakakis N., Ghaly W., and Mantzoros C., “Obesity as a Disease,” Medical Clinics of North America Journal, 102(1): 13-33, January 2018.
Perakakis N., Ghaly W., Peradze N., Boutari C., Batirel S., Douglas V.P., and Mantzoros C., Research Advances in Metabolism 2017, Metabolism. 2018 Jun;83:280-289.
Ammar H.I., Saba S., Ammar R.I., Elsayed L.A., Ghaly W., and Dhingra S., “Erythropoietin Protects Against Doxorubicin-induced Heart Failure,” American Journal of Physiology- Heart and Circulatory Physiology, 301(6):H2413-21, December 2011.
Regulation of the activins-follistatins-inhibins axis by energy status: Impact on reproductive function
Physiology of Activins/Follistatins: Associations With Metabolic and Anthropometric Variables and Response to Exercise
Follistatins in glucose regulation in healthy and obese individuals
Circulating levels of gastrointestinal hormones in response to the most common types of bariatric surgery and predictive value for weight loss over one year: Evidence from two independent trials
Targeted Analysis of Three Hormonal Systems Identifies Molecules Associated with the Presence and Severity of NAFLD.
Omega-3 Polyunsaturated Fatty Acids Provoke Apoptosis in Hepatocellular Carcinoma through Knocking Down the STAT3 Activated Signaling Pathway: In Vivo and In Vitro Study.
Ascorbic acid alleviates oxidative stress and improves major salivary glands’ structure and function in diabetic rats: A histological and immunohistochemical study.