Faculty of Science

Prof.Dr. Abdelmoneim Abdelsalam Makhlouf

Contact Information
Phone number : 084 6338462 - 084 6344264
Fax number : 084 6370025
E-mail Address : aam11@fayoum.edu.eg
Office : Chemistry Department - Faculty of Science - Fayoum University
Post Address : Fayoum - Fayoum University - faculty of science - chemistry Department - POBox: 63514
Academic Qualifications
B.Sc.: Chem./Geology, Cairo University, 1966
M. Sc.: Organic Chem., Fac. of Science, Alazhar University,1976
Ph.D.: Organic Chem., Fac. of Science, Alazhar University,1979
Academic Positions
Lecturer: 1983
Assistant Professor:1989
Professor:2005
Research Interests
Synthesis of heterocyclic compounds with expected biological & pharmacological importance
Organic syntheses using echo-friendly approaches
Synthesis of pharmaceutical intermediates
Chemistry and reactions of amino acids and peptides
List of Publications
Synthesis of 2-furoyl-, 2-thenoyl- and 3,4,5-trimethoxybenzoyl- amino acid derivatives. A. M. El-Naggar, M. O. Abdel-Rahman and A. A. Makhlouf. Roczniki Chem.,50 (12), 2175 (1976).
Synthesis of some –N-(2-phenyl-2-cyclopentylacetylamino) and -N-(2-phenyl-2-cyclo-hexylacetylamino)acid derivatives A. M. El-Naggar, M. O. Abdel-Rahman and A. A. Makhlouf. Indian J.Chem., 15 (11), 1066(1977).
Synthesis of some substituted 3-(2-thienyl)-acryloylamino acid derivatives. A. M. El-Naggar, M. N. Aboul-Enein and A. A. Makhlouf. Bull. Soc. Chim. Beograd, 46 (10), 545 (1981).
Synthesis of some 2-thenoyl-, 5-bromo-2-thenoyl- and 5-nitro-2- thenoylamino acid derivatives and their antimicrobial activity. A. M. El-Naggar, M. N. Aboul-Enein and A. A. Makhlouf J. Indian Chem. Soc., 59, 783 (1982).
A simple manufacturing procedure of the insecticide 2-isopropoxyphenyl-N-methylcarbamate “propoxur”. M.N.Aboul-Enein, M.M.Sidky, H.I.Heiba and A.A.Makhlouf. Bull. NRC, Egypt, 6, 381 (1981).
Synthesis of 2-methoxybenzylpyrrolidines of analgesic potential. M. N. Aboul-Enein, S. M. El-Difrawy, K. Z. Gadallah, A. A. Makhlouf and M. E. El-Sayed., Acta Pharm. Suec., 22, 53 (1985).
1-Sustituted 1,4-diazaspiro[4,5]decane- and 1,4-diazaspiro[5,5] undecane-3-imino-5-ones as anticonvulsantes M. N. Aboul-Enein, A. A. El-Azzouny, S. H. Mohamed and A. A. Makhlouf., Sci. Pharm., 55, 77 (1987).
Synthesis of ethyl 1-(1-phenylcyclohexyl) –4-phenylpiperidine- 4-carboxylate as potential analgesic. M. N. Aboul-Enein, A. A. Makhlouf and A. A. El-Azzouny Sci. Pharm., 56, 77 (1987).
Synthesis of 17 –keto-androsteno heterocycles. F. M. Abdel-Galil, A. A. Makhlouf and T. S. Abdin. 2nd IBN SINA Symposium on Heterocyclic Chemistry, November(1988).
New 4-substituted phthalazinone derivatives of possible antibacterial activity. E. M. M. Kassem, M. M. Kamel, A. A. Makhlouf and M.T.Omar. Pharmazie, 44 (1), 62 (1989).
Synthesis and analgesic properties of some 1-anilidocyclo- hexane carboxamides. M. N. Aboul-Enein, A. A. El-Azzouny and A. A. Makhlouf. Egypt. J. Pharm. Sci., 30 , 291 (1989).
Piperidyl and quinoclidinyl esters of 1-benzanilidocyclohexane- carboxylic acids as analgesics. M. N. Aboul-Enein, A. A. El-Azzouny, N. A. Abdallah, A. A. Makhlouf and W. Werner., J. I. A. Sci. 2, 34 (1989).
Synthesis of 1-alkyl-2-methoxybenzylpyrrolidinol esters of analgesic activity. M. N. Aboul-Enein, S. M. El-Difrawy, K. Z. Gadallah, A. A. Makhlouf and M. E. El-Sayed., Egypt. J. Pharm.Sci., 31, 29 (1990).
Synthesis of certain spirohexahydro-4,7-methanoindanpiperazine derivatives as analgesics. M.N.Aboul-Enein, A.A.Makhlouf and A.A.El-Azzouny. Sci. Pharm., 58, 263 (1990).
Synthesis and local anaesthetic activity of certain basic esters of 1-dialkylaminocyclohexyl carbinols. M. N. Aboul-Enein, A. A. El-Azzouny, N. A. Abdallah and A. A. Makhlouf., Egypt. J. Chem. 34, 549 (1991).
Synthesis of some basic ethers of 6-arylidenehexahydro-4,7- methano- indan-5-one oximes and their salts as local anaesthetics. M. N. Aboul-Enein, A. A. Makhlouf, A. A. El-Azzouny and N. A. Abdallah., Sci. Pharm. 60, 57 (1992).
Synthesis of some 6-(alkylamino)methyl hexahydro-5-aryl-and aralkyl-4,7-methanoindan-5-ols and certain of their propionate esters as analgesics. M. N. Aboul-Enein, A. A. El-Azzouny, N. A. Abdallah, S. M. Moharam, W. Werner, A. Eid and A. A. Makhlouf. J. I. A. Sci., 6 , 99 (1993).
Synthesis of certain 5-piperidyl-1,3,4-oxadiazol-2(3H)-ones & - 2(3H)-thiones. M. N. Aboul-Enein, A. A. El-Azzouny, N. A. Abdallah, O.M. El- Shabrawy, A. A. Makhlouf and W. Werner. Sci. Pharm. 63, 175 (1995).
New Antimicrobial Quinazolinone Derivatives.I.F.Zeid, M.T.Omar, A.A.Makhlouf, M.M.Kamel and N.M.Khalifa. Egypt. J. Pharm. Sci. 37 , 251 (1996).
New Antimicrobial Rhodanines. A.A. Makhlouf and A. S. Mohamed., Pharmazie,51, 430(1996).
7-Hydroxy-5-Methyl Thiazolo[5,4-b]Pyridine in the Mannich Reaction. A.A. Makhlouf and M.M. Kamel., Egypt. J. Chem. 45 (1), 225 (2002).
Synthesis and Analgesic-Antiinflammatory Activity Of Some 1,2,4 - Triazine Derivatives. Abdelmoneim A. Makhlouf and Yousreya A. Maklad. Arzneim.-Forsch./Drug Research, 54 (1), 42 (2004).
Synthesis and Biological Evaluation of Certain N-Benzyl-N- (1-piperidin-1-yl-cyclohexyl methyl)-Benzamides. M. N. Y. Aboul-Enein, A. A. El-Azzouny, A. A. Makhlouf and Y.A. Maklad., Egypt. J. Pharm. Sci. NRC, 3, 19 (2004).
New 5-Oxo-imidazoline Schiff Bases and Other Related Compounds as Inhibitors of Bilharzia Snail’s Ovulation. Abdelmoneim A. Makhlouf, M. M. Kamel and M. I. El-Zahar. Egypt. J. Chem. 48, 135 (2005).
Synthesis of Some New 1,8-Naphtharidine-3-carboxamides of Possible Antimicrobial Activity. A. A. Makhlouf, M. M. Kamel, M. M. Anwar, M. E. Haiba and E.M. Mohei El-Deen., Egypt. Pharm. J. 4, 371 (2005).
Studies With 3-Functionally Substituted 2-Arylhydrazononitriles: A New Route to 3- substituted -2-Arylhydrazononitriles, 4-Amino- pyrazole-5-carbonitriles, Azadienes and Cinnolines. R. M. Abdel-Motaleb, A.-M. A.-S. Makhlouf, H. M. Ibrahim and M. H. Elnagdi. , J. Heterocycl. Chem., 43, 931(2006).
Studies With Azoles and Benzazoles: A Novel Simple Approach for Synthesis of 3-Functionlly Substituted 3-Acylindoles. R. M. Abdel-Motaleb, A.-M. A.-S. Makhlouf, H. M. Ibrahim and M. H. Elnagdi., J. Heterocycl. Chem., 44, 109 (2007).
Utility of Cyanoacetamides As Precursors To Pyrazolo-[3,4-d]- Pyrimidine-4-ones, 2-Aryl-6-substituted-1,2,3-triazzolo[4,5-d]- Pyrimidines and Pyrazolo[1,5-a]Pyrimidine-3-carboxamides. H. M. Ibrahim , S. Makhseed, R. M. Abdel-Motaleb, A.-M. A.-S. Makhlouf, and M. H. Elnagdi., J. Heterocyclic Chem., 44, (2007).