Alzheimer's disease

Organizers: Ibrahim Mohamady Ibrahim and Shaimaa Nasr Amin

Alzheimer's disease (AD) is the most common cause of dementia where the loss of intellectual and social abilities severe enough to interfere with daily functioning. In Alzheimer's disease, healthy brain tissue degenerates, causing a steady decline in memory and mental abilities.

The aim of the symposium is to highlight the different theories explaining the aetiology of Alzheimer's disease, and recent pharmacological work in management of AD

The symposium will start by presentation on pathophysiology of AD focussing on neurons and synapse loss in cortex and hippocampus, abnormalities in neurotransmitter system and future memory and cognitive enhancers.

Then evidences and theories explaining new neurovascular concept of AD will be discussed with findings from a recent study conducted in Cairo University on atherosclerosis and cerebral blood flow dysregulation in AD which support this concept. Identification of arterial tree abnormalities in Alzheimer's disease assessed by extracranial ultrasonography and transcranial color coded duplex (TCCD) will be discussed and the last presentation will focus on recent advances in drug therapy used in management of AD.

Speakers and Topics

Pathophysiology of Alzheimer's disease.
Tarek Mahmoud Shoukry, Lecturer of Medical Physiology, Faculty of Medicine, Cairo University

Vascular Factors in Alzheimer's Disease.
Azza Abbas Helmy, Professor of Neurology, Faculty of Medicine, Cairo University

Arteriopathy in Alzheimer's disease.
Marwa Farghaly, Lecturer of Neurology, Faculty of Medicine, Cairo University

Recent advance in drug therapy in Alzheimer's disease.
Abd el Fattah Marei, Professor of Pharmacology, Faculty of Medicine-Cairo University